Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B

Structure of phosphorylated Thr160 CDK2/cyclin A in complex with the inhibitor variolin B Descriptor: 9-amino-5-(2-aminopyrimidin-4-yl)pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidin-4-ol, Cell division protein kinase 2, Cyclin-A2, ... Authors: Echalier, A, Bettayeb, K, Ferandin, Y, Lozach, O, Clement, M, Valette, A, Liger, F, Marquet, B, Morris, J.C, Endicott, J.A, Joseph, B, Meijer, L. Deposit date: 2007-11-29 Release date: 2008-02-12 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Meriolins, a new class of cell death inducing kinase inhibitors with enhanced selectivity for cyclin-dependent kinases Cancer Res., 67, 2007