Comparison between Lavender and Chamomile in Essential Oil for Pain and Anxiety Reduction during Amniocentesis in Second Trimester Pregnancy; A Randomize Controlled Trial

Objective: The purpose of this study was to investigate effectiveness of aromatherapy (lavender and chamomile essential oils) to alleviate pain and reduce anxiety during the amniocentesis procedure in second trimester pregnancy

Education level

1 Primary level

2 Secondary level

3 Bachelor level

History of surgery

1 Yes

2 No

History of amniocentesis 

0 Yes

1 No

Indication of amniocentesis

1 Advance age

2 Chromosome abnormalities 

3 Abnormal PND

4 Patient need

Pain1 : Expected VAS before amniocentesis 

Pain2 : VAS during amniocentesis 

Pain3 : VAS at 15 minutes after amniocentesis 

Pain4 : VAS at 30 minutes after amniocentesis 

Anxiety1 : Expected VFAS before amniocentesis 

Anxiety2 : VFAS during amniocentesis 

Anxiety3 : VFAS at 15 minutes after amniocentesis 

Anxiety4 : VFAS at 30 minutes after amniocentesis