Rachel Fink, Pat Wadsworth (2011) CIL:35202, Fundulus heteroclitus, epithelial cell. CIL. Dataset

This video shows the apical (outside-facing) side of epithelia cells that form confluent tissues where each cell is tightly glued to its neighbors by circumferential junctions like bands of velcro. These cells show that the cell surface is extremely dynamic, blistering and boiling with small surface protrusions, filled with actin. This video also shows these protrusions in parts of three neighboring cells, and the circumferential actin-filled ridges at the cell margins are particularly dramatic. The actin used in these protrusions is the same pool used by deep cells for individual migration, and these enveloping (EVL) cells use the same kinds of biochemical controls for polymerization (rapid growth) and depolymerization (shrinkage) of filaments.

本视频展示了构成连续组织的上皮细胞顶侧（面向外侧）的形态，其中每个细胞通过环绕式的粘合连接，如同魔术贴般紧密地与其相邻细胞相连。这些细胞显示出细胞表面极具动态性，表面出现泡状突起，充满肌动蛋白。此外，视频还展示了三个相邻细胞部分区域的这些突起，以及细胞边缘环绕的充满肌动蛋白的环形脊显得尤为引人注目。在这些突起中使用的肌动蛋白与深层细胞用于个体迁移的肌动蛋白来自同一储存池，而包围性（EVL）细胞在微丝聚合（快速生长）和去聚合（收缩）的生化调控方面也采用相同的方式。