RB modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions

NIAID Data Ecosystem2026-05-10 收录

染色质三维结构调控

增强子-启动子互作

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE246946 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-09-30

BACH1 Recruits NANOG and Histone H3 Lysine 4 Methyltransferase MLL/SET1 Complexes to Regulate Enhancer-promoter Activity and Maintains Pluripotency

胚胎干细胞多能性调控

增强子-启动子互作

Maintenance of stem-cell identity requires proper regulation of enhancer activity. Both transcription factors OCT4/SOX2/NANOG and histone methyltransferase complexes MLL/SET1 were shown to regulate en

NIAID Data Ecosystem80

Cell type and expression independent spatial enhancer-promoter proximity. Cell type and expression independent spatial enhancer-promoter proximity

增强子-启动子互作

HiChIP染色质构象捕获

We explored the relationship between enhancer-promoter pairs, spatial proximity and cell specific gene expression Overall design: We performed HiChIP using the H3K27ac antibody in two cell lines, Endo

NIAID Data Ecosystem40

The impact of genomic distance on enhancer-promoter interactions at the CFTR locus.

增强子-启动子互作

CFTR基因表达调控

We identified and characterized multiple cell-type selective enhancers of the CFTR gene promoter in previous work and demonstrated active looping of these elements to the promoter. Here we address the

NIAID Data Ecosystem10

Enhancer-promoter interactions in acheiropodia patient's cells

先天性肢体截断

增强子-启动子互作

Acheiropodia, congenital limb truncation, is associated with homozygous deletions in the LMBR1 gene around ZRS, an enhancer regulating SHH during limb development. How these deletions leads to this ph

NIAID Data Ecosystem60

RNA polymerase II pausing contributes to maintain chromatin organization in erythrocytes [Hi-C]. RNA polymerase II pausing contributes to maintain chromatin organization in erythrocytes [Hi-C]

染色质三维结构调控

血细胞终末分化

Chicken erythrocytes are nucleated cells often referred to as transcriptionally inactive, although the epigenetic changes and chromatin remodeling that mediate transcriptional repression and the exten

NIAID Data Ecosystem20

RB modulates chromatin organization by regulating cohesin-dependent loops and enhancer-promoter interactions

资源简介：

相关数据集