Estimates of killing rates based on a model with a saturating killing term for in vivo CTL killing data.

The parameters and are estimated based on the in vivo CTL killing data from Barber et al. [5]. The numbers in brackets represent 95%-confidence intervals based on 1000 bootstrap samples. The correspond to an which compares these estimates with the results of fitting the data to a model with a mass-action assumption in the killing term. and correspond to the mean frequency of epitope-specific CTL measured in the spleen and among CD8+ T cells in the spleen, respectively together with their 95%-confidence intervals.