Crystal structure of human PARP1 ART domain bound to inhibitor UKTT22 (compound 14)
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Crystal structure of human PARP1 ART domain bound to inhibitor UKTT22 (compound 14) Descriptor: (2P)-2-{3-[(2-amino-4,5-dimethylphenyl)carbamoyl]phenyl}-1H-benzimidazole-4-carboxamide, 1,2-ETHANEDIOL, CITRIC ACID, ... Authors: Rouleau-Turcotte, E, Pascal, J.M. Deposit date: 2023-01-27 Release date: 2024-02-07 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Novel modifications of PARP inhibitor veliparib increase PARP1 binding to DNA breaks. Biochem.J., 481, 2024
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2023-01-27
