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A Novel Strategy for Combination of Clofarabine and Pictilisib is Synergistic in Gastric Cancer

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174288
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Purpose: We aimed to identify a novel therapeutic approach in gastric cancer using high-throughput screening and our computational SynerySeq pipeline. We investigated the therapeutic efficiency of clofarabine as a single agent and in combination with the PI3K inhibitor pictilisib in treating in vitro and in vivo models of gastric cancer. Examination of 2 gastric adenocarcinoma cell lines AGS and MKN45 treated with Clofarabine compound
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2022-01-31
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