TAILS N-terminomic and proteomic datasets of the Human Odontoblast Cell Layer and comparison with the Dental Pulp Proteome and N-Terminome
收藏Mendeley Data2024-03-27 更新2024-06-26 收录
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Supplementary Tables for: Comparison of the Human Odontoblast Cell Layer and Dental Pulp Proteomes and N-Terminomes. Simon R. Abbey1,*, Ulrich Eckhard1,2,*, Giada Marino1,2, Nestor Solis1,2, Ian Matthew1, and Christopher M. Overall1,2,3,‡ * 1 Department of Oral Biological and Medical Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, BC, Canada, V6T 1Z3 * 2 Centre for Blood Research, University of British Columbia, Vancouver, BC, Canada, V6T 1Z3 * 3 Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, Canada, V6T 1Z3 * *These authors contributed equally. * ‡ To whom correspondence should be addressed. Email: chris.overall@ubc.ca The Data described here provide the in-depth proteomic and N-terminomic assessment of the human odontoblast cell layer by the positional proteomics technique TAILS (Terminal Amine Isotopic Labelling of Substrates) N-terminomics. All LC-MS/MS datasets were analyzed using four different database search engines in combination with statistical downstream evaluation. All raw data and the corresponding metadata have been deposited in ProteomeXchange with the PXD identifier ˂PXD006557˃. Please see also our data on dental pulp deposited on ProteomeXchange with the identifier ˂PXD002264˃, our publication in the Journal of Proteome Research (doi:10.1021/acs.jproteome.5b00579), and the respective Supplementary tables at Mendeley Data (http://dx.doi.org/10.17632/555j3kk4sw.1).
配套附表:人成牙本质细胞层与牙髓蛋白质组及N-端蛋白质组的比较研究。Simon R. Abbey1,*, Ulrich Eckhard1,2,*, Giada Marino1,2, Nestor Solis1,2, Ian Matthew1 及 Christopher M. Overall1,2,3,‡ * 1 英属哥伦比亚大学牙医学院口腔生物与医学科学系,加拿大不列颠哥伦比亚省温哥华,V6T 1Z3 * 2 英属哥伦比亚大学血液研究中心,加拿大不列颠哥伦比亚省温哥华,V6T 1Z3 * 3 英属哥伦比亚大学生物化学与分子生物学系,加拿大不列颠哥伦比亚省温哥华,V6T 1Z3 * * 本文作者贡献均等。 ‡ 通讯作者,电子邮箱:chris.overall@ubc.ca 本数据集所载内容为通过位置性蛋白质组学技术TAILS(底物末端胺同位素标记N-端蛋白质组学,Terminal Amine Isotopic Labelling of Substrates N-terminomics)对人成牙本质细胞层开展的深度蛋白质组学与N-端蛋白质组学分析。所有LC-MS/MS(液相色谱-串联质谱)数据集均结合四种不同的数据库搜索引擎进行分析,并辅以下游统计验证。所有原始数据及对应元数据已提交至ProteomeXchange(蛋白质组交换数据库),登录编号为<PXD006557>。另请参阅我们提交至ProteomeXchange、登录编号为<PXD002264>的牙髓相关数据集,发表于《Journal of Proteome Research》(《蛋白质组研究杂志》)的研究论文(DOI: 10.1021/acs.jproteome.5b00579),以及存放在Mendeley Data的相关配套附表(http://dx.doi.org/10.17632/555j3kk4sw.1)。
创建时间:
2024-01-23
搜集汇总
背景与挑战
背景概述
该数据集提供了人类成牙本质细胞层的深度蛋白质组和N末端组学数据,使用TAILS技术进行分析,并与牙髓组织的蛋白质组和N末端组学进行比较。数据已公开存储在ProteomeXchange(标识符PXD006557),并与相关研究(PXD002264)和出版物相关联,支持牙科生物医学研究。
以上内容由遇见数据集搜集并总结生成



