Lipid-induced granule assembled by DDX49 in hepatocytes restrains liver fibrosis

NIAID Data Ecosystem2026-05-10 收录

纤维化分子机制

细胞脂质代谢

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Original raw data for“Lipid-induced granule assembled by DDX49 in hepatocytes restrains liver fibrosis”

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2025-12-09

RNA-sequencing of TGF-ß1-driven gene expression in human kidney cell line. Homo sapiens

纤维化分子机制

TGF-ß1转录组分析

TGF-beta1 is the major cytokine driver of fibrotic scarring observed in diabetic nephropathy and other fibrosis-related diseases. RNA-sequencing offers the potential for more sensitive assessment of t

NIAID Data Ecosystem110

Novel targets in renal fibrosis based on bioinformatic analysis II

纤维化分子机制

生物标志物发现

Renal fibrosis is a widely used pathological indicator of progressive chronic kidney disease (CKD), and renal fibrosis mediates most progressive renal diseases as a final pathway. Nevertheless, the ke

NIAID Data Ecosystem70

Additional file 14: Table S7. of A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis

HBV相关肝癌

纤维化分子机制

HBV integration sites identified in BGI, TCGA, and ICGC cohorts. (XLSX 92 kb)

NIAID Data Ecosystem60

Chitinase-3 Like 1 Is a Profibrogenic Factor Overexpressed in Aging Livers and in Patients with Cirrhosis in the Aging Liver and in Patients with Liver Cirrhosis

纤维化分子机制

衰老相关基因表达

Older age at the time of infection with hepatitis viruses is associated with an increased risk of liver fibrosis progression, but the mechanisms remain unclear. We hypothesized that the pace of liver

NIAID Data Ecosystem90

Next Generation Sequencing of Lung Primary Fibroblast Responding to Eosinophil-Degranulation Products

纤维化分子机制

细胞-成纤维细胞互作

Methods: Two human lung primary fibroblast (HLF) lines were activated for 24 h with eosinophil conditioned media obtained from two blood eosinophil donors. Total RNA was extracted from HLF and treated

NIAID Data Ecosystem60

Lipid-induced granule assembled by DDX49 in hepatocytes restrains liver fibrosis

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