The minimal gene set for life has often been theorised, with at least ten produced for Mycoplasma genitalium (M. genitalium). Due to the difficulty of using M. genitalium in the lab, combined with its
(A) Gap-filling: a gap (with N’s) is replaced with the corresponding sequence (e.g., ATGCTA). (B) Splitting: A contig is split into two sequences at the zero-coverage position. (C) Representative sequ
This repository contains the data used to train the ML surrogates presented in the paper 'Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning
Next-generation sequencing (NGS) technologies have revolutionized phylogenomics by decreasing the cost and time required to generate sequence data from multiple markers or whole genomes. Further, the