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Methylation and chromatin abnormalities in chronic myelomonocytic leukemia.

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP277843
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资源简介:
In this study, institutional IRB approval was obtained and peripheral blood and bone marrow samples on patients with chronic myelomonocytic leukemia were collected. On the samples, we performed chromatin immuno-precipitation and next generation sequencing to assess histone modifications and epigenetic changes associated with proliferative and dysplastic phenotypes. Overall design: Samples were collected from the bone marrow after obtaining written informed consent. This was approved by the Mayo Clinic IRB 15-003786
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2021-04-01
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