Interventions: On Day 1, patients treated with FOLFIRI therapy received a 2-hour intravenous infusion of CPT-11 (150 mg/m2) combined with 1-LV (200 mg/m2), followed by a rapid intravenous infusion of
Demographic data Study Description This was a phase I, open-label, pharmacokinetic (PK) study with a primary objective of determining PK of sildenafil in premature infants. The trial enrolled 25 prema