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Women with the Alzheimer's risk marker ApoE4 lose Abeta-specific CD4⁺ T cells 10-20 years before men.

Name: Women with the Alzheimer's risk marker ApoE4 lose Abeta-specific CD4⁺ T cells 10-20 years before men.
Creator: IEDB
Published: 2014-01-01T00:00:00+08:00

ImmuneData2026-05-21 收录

神经免疫学

阿尔茨海默病生物标记物

数据链接：

https://immunedata.org/display-item.php?repository=0009&id=AWPUDSmsh18v6WY6RqLS&query=%20 数据链接链接失效反馈

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Proliferation was measured using CSFE-loaded cells.

应用场景：

提供机构：

IEDB

创建时间：

2014-01-01

神经免疫学

单细胞转录组学

3D viSNE representation of microglial modules: DAM (Red) and Homeostatic (Black) genes identified by single-cell RNAseq mapped to WGCNA modules. (HTML 3818 kb)

Figshare2018-05-22 更新50

Additional file 1 of Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease

阿尔茨海默病生物标记物

神经元可塑性

Additional file 1: Data S1. Participant characteristics. S1a: Characteristics of individuals with CSF Aβ1-42 and tau measurements available; S1b: Characteristics of individuals with CSF proteomic data

Figshare2024-02-06 更新40

Selective pre-priming of HA-specific CD4 T cells restores immunological reactivity to HA on heterosubtypic influenza infection.

免疫应答

CD4T细胞反应

CD4 T cell responses directed against the epitope were greatly diminished in the spleen at 8 days following secondary infection compared to the responses following a primary infection.

ImmuneData30

Assessment of seasonal influenza A virus-specific CD4 T-cell responses to 2009 pandemic H1N1 swine-origin influenza A virus.

流感病毒免疫

疫苗效果评估

The epitope specific CD4+ T cell line proliferated in response to the Fluzone vaccine formulation from 2004-2005.

ImmuneData40

Loss in CD4 T-cell responses to multiple epitopes in influenza due to expression of one additional MHC class II molecule in the host.

T细胞免疫应答

MHC限制性

The epitope sequence was cited in Nayak et al. Viral Immunol. 2010 Apr;23(2):169-80 [PMID:20373997]. Similar results were seen for (B10 x B10.S) F1 mice (H-2bxs). Also, little apparent difference was

ImmuneData30

Women with the Alzheimer's risk marker ApoE4 lose Abeta-specific CD4⁺ T cells 10-20 years before men.

资源简介：

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