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HCP5 inhibits apoptosis via c-Myc transcriptional regulation mediated by UTP3 based chromatin-RNA-binding protein interaction [RNA-Seq]

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NIAID Data Ecosystem2026-03-14 收录
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This study demonstrates that HCP5/UTP3/c-Myc/VAMP3 axis plays important role in inhibition of cancer cell apoptosis and HCP5 can be targeted to contribute to cell apoptosis induced by cytotoxic agents. Overall design: RNA-seq of HCP5-silenced and control KYSE150 and KYSE510 cells

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2022-10-27
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