Structure of PP5C with LB-100; 7-oxabicyclo[2.2.1]heptane-2,3-dicarbonyl moiety modeled in the density
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Structure of PP5C with LB-100; 7-oxabicyclo[2.2.1]heptane-2,3-dicarbonyl moiety modeled in the density Descriptor: (1S,2R,3S,4R)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ... Authors: D'Arcy, B.M, Swingle, M.R, Honkanen, R.E, Prakash, A. Deposit date: 2017-07-13 Release date: 2018-07-18 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.65 Å) Cite: The Antitumor Drug LB-100 Is a Catalytic Inhibitor of Protein Phosphatase 2A (PPP2CA) and 5 (PPP5C) Coordinating with the Active-Site Catalytic Metals in PPP5C. Mol. Cancer Ther., 18, 2019
创建时间：
2017-07-13
