The ileal microbiome and mucosal immune profiles in response to dietary supplementation of ultra-grinded Astragalus membranaceus in weaned goats

Given that the ileum represents a site for nutrient absorption and intestinal microbial and immune function of the small intestine, we hypothesized that supplementation of ultra-grinded A. membranaceus (UGAM) powder might improve the microbiota composition, tight junction, and immune functions of the ileum. This study aimed to assess the effects of feeding a basal diet supplemented with UGAM on the blood metabolites, and immune function, tight junction and microbiota composition in the ileum of weaned goats.