Differentially expressed genes in synovial tissue on days 3 and 14.

Synovial tissue was harvested at baseline, 3- and 14-days post-injury/bleed with treatment by Saline (vehicle), rhFVIII, or mFcFVIII. Limma DGE analysis was performed (see Methods) between injured-saline vs baseline (day 3 or 14) samples, between injured-saline vs injured-rhFVIII, and injured-saline vs injured-mFcFVIII samples. The significant genes, with adjusted p-value <0.05, are listed for each comparison along with logFC and results from statistical analysis. DGE, differential gene expression; LogFC, Log-fold change. (XLSX)