A goal of a collaboration between the CHDI Foundation and Prof. Jenny Morton at Cambridge University was to identify genes in mice with diurnal/circadian expression patterns. Tissues from wild type mi

NIAID Data Ecosystem50

Time-course whole brain transcriptome and methylome profiles of early life high GC exposed zebrafish. Optogenetic glucocorticoid elevation in early-life alters adult behaviors and primes brain-wide transcriptional alteration in zebrafish

神经内分泌应激反应

早期生命编程

Whole-brain transcriptome (mRNA) profiles of zebrafish which exposed to elavated glucocorticoid (GC) optogenetically at 6, 13, 120 day-post-fertilization (dpf), and post-predatory stress (looming dots

NIAID Data Ecosystem10

Figure 5: Serum corticosterone and hippocampal GR expression levels after DSR testing.

神经内分泌应激反应

社会行为分子机制

48 hours following behavioral testing, DSR-exposed mice of both strains demonstrated significantly reduced basal serum corticosterone concentrations, regardless of strain (A). Hippocampal expression o

NIAID Data Ecosystem90

Transcriptome analysis of Chd8 S62X heterozygote mutant and wild-type mice

发育疾病机制

大鼠转录组学

Autism spectrum disorders (ASD) are ~4-times more common in males than females, and CHD8 (a chromatin remodeler)-related ASD shows a strong male bias (~5:1), although the underlying mechanism remains

NIAID Data Ecosystem40

Novel aspects of the transcriptional stress response in the paraventricular nucleus of the mouse strains DBA/2J and C57BL/6J

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