Active conformation of EGFR kinase in complex with BI-4020

Active conformation of EGFR kinase in complex with BI-4020 Descriptor: (20R)-10,15,20-trimethyl-2-[(4-methylpiperazin-1-yl)methyl]-18,19,20,21-tetrahydro-15H,17H-12,8-(metheno)pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-7(6H)-one, CHLORIDE ION, Epidermal growth factor receptor Authors: Beyett, T.S, Eck, M.J. Deposit date: 2020-12-06 Release date: 2022-01-19 Last modified: 2024-05-29 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Analysis of the Macrocyclic Inhibitor BI-4020 Binding to EGFR Kinase. Chemmedchem, 2024