Influence of N276D in different Envs on their sensitivity to various entry inhibitors in TZMbl assay.
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aThe Envs from VI1090 (CRF02_AG), 92RW009.6 (subtype A) and VI829 (subtype C) were either used as such (WT) or after site-directed mutagenesis at the 276 position to construct PV for the TZMbl assay.bMean IC50 (µg/ml) of at least two (VRC01 and VRC03) or three (all others) independent experiments are shown.
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2015-12-02
