Comparison profiles of RNA m6A and DNA methylation between mouse female germline stem cells and STO cells

In this study, epigenetic differences such as DNA methylation and mRNA m6A modification in STO and FGSCs were comprehensively analyzed and compared, and specific binding of Stella and histone modification in FGSCs was combined to find that DNA methylation and mRNA m6A as well as transcription factor Stella might be related to FGSCs cell characteristics. Overall design: mRNA m6A and DNA methylation profiles of FGSCs and STO cells ,and the ChIP-Seq of Stella and H3K27me3, H3K27ac, H3K4me1,H3K4me3 were generated by deep sequencing, in duplicate.