IGF1R mutant rat sequencing

Figshare2025-09-19 更新2026-04-28 收录

基因敲除模型

动物基因测序

数据链接：

https://figshare.com/articles/dataset/IGF1R_mutant_rat_sequencing/27853899 数据链接链接失效反馈

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资源简介：

Sequencing results of transgenic rats harboring a disruption in the IGF1R sequence to create a knockout allele.

创建时间：

2025-09-19

Gene expression data from the skin of Cdsniep-/-adult mice. Mus musculus

疾病分子机制

基因敲除模型

Peeling Skin Disease (PSD; OMIM 270300) is an inflammatory ichthyosis due to homozygous loss-of-function mutations in Corneodesmosin (CDSN) and characterized by lifelong patchy peeling of the skin ass

NIAID Data Ecosystem60

DIA quantification proteomics to compare protein expression differences in the hippocampus of wild-type and Mdga2 +/− mice.

神经细胞蛋白质组学

基因敲除模型

DIA quantification proteomics to compare protein expression differences in the hippocampus of wild-type and Mdga2 +/− mice.

Figshare2025-04-01 更新40

RNA-Seq of Ctrl, Myocd KO, Mrtfa/b DKO and TKO cardiomyocytes

心肌细胞转录组学

基因敲除模型

To characterize transcriptome changes uopn Myocd KO, Mrtfa/b DKO and Mrtfa/b/Myocd TKO in maturing cardiomyocytes Overall design: AAV-Cre or AAV-Myocd-sgRNAwere injected into P1 Rosa-Cas9GFP or Mrfta

NIAID Data Ecosystem40

Transcriptome profiling of murine aortic Vascular Smooth Muscle cells from ApoE knockout and ApoE/Neil3 double knockout mice. Transcriptome profiling of murine aortic Vascular Smooth Muscle cells from ApoE knockout and ApoE/Neil3 double knockout mice

平滑肌细胞转录调控

基因敲除模型

We performed high-throughput RNA sequencing to characterize possible differences in the transcriptome of murine aortic Vascular Smooth Muscle cells from both 26 weeks-old ApoE knockout and ApoE/Neil3

NIAID Data Ecosystem50

Serum levels of PGE 2 in wild-type and IVA-PLA 2 -knockout mice.

脂代谢炎症研究

基因敲除模型

Wild-type and IVA-PLA2-knockout (KO) mice were fed normal (N) or high-fat (HF) diets for 16 weeks and fasted. The serum levels of PGE2 were measured (n = 3–5). aP<0.05 versus wild-type mice fed normal

NIAID Data Ecosystem40

IGF1R mutant rat sequencing

资源简介：

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