HLA Class I alleles that specifiy recognition of conserved HIV sequences protect from neurocognitive impairment and decline.

Values (other than sample N) in tables represent averages of the indicated variables. BL is baseline score and 012 is twelve month evaluation point. “Decline” is significant neurocognitive decline between BL and 012 (see methods). GDS is ‘global deficit score’ and neurocognitive impairment is defined as ≥0.5. Percent ART is percentage of group on at least 2 anti-retroviral medications. CD4 and CD8 value are absolute cells/microliter. HRNA log is log value of HIV RNA copies/ml with a lower limit of detection of 50 copies. All statistical tests are two tailed, values