Supplemental Data: Activation of α-7 Nicotinic Acetylcholine Receptor Reduces Ischemic Stroke Injury through Reduction of Pro-Inflammatory Macrophages and Oxidative Stress
Microglia, the resident immune cells of the brain, are crucial in the development of the nervous system. Recent evidence demonstrates that microglia modulate adult hippocampal neurogenesis by inhibiti
A role for microglia in neuropsychiatric diseases, including major depressive disorder (MDD) has been postulated. Regulation of microglial phenotype by immune receptors has become a central topic in m
With increasing age microglia shift toward a pro-inflammatory phenotype and become hyperresponsive to inflammatory stimuli, disrupting brain homeostasis. Soluble fibers have been suggested as a dietar
Microglia are brain-resident, myeloid cells that play important roles in health and brain pathologies. While data on chromatin accessibility in activated murine microglia are available, there is no su
BackgroundStroke is one of the most severe diseases worldwide, resulting in physical and mental problems. Dl-3-n-butylphthalide, a compound derived from celery seed, has been approved for treating isc
