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Adenylation domain of NAD+ dependent DNA ligase from M.tuberculosis

NIAID Data Ecosystem2026-05-01 收录

结核分枝杆菌酶

药物靶点发现

数据链接：

https://www.rcsb.org/structure/1ZAU 数据链接链接失效反馈

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Adenylation domain of NAD+ dependent DNA ligase from M.tuberculosis

应用场景：

创建时间：

2024-02-14

蛋白质晶体学

药物靶点发现

Crystal structure of DYRK1A complexed with FC162 inhibitor Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 8-cyclopropyl-2-pyridin-3-yl-[1,3]thiazolo[5,4-f]quinazolin-9-one, DIMETHYL

Protein Data Bank Japan2024-11-06 更新50

GEO_submission_RNAseq_yangyiren

药物靶点发现

转录组学分析

By comparing the transcriptome data of con group and drug group, we can find the relevant targets and pathways.

NIAID Data Ecosystem30

IMPRINTS-CETSA Docetaxel and Paclitaxel in MCF-7 cells, 8h incubation

药物靶点发现

化疗疗效评估

IMPRINTS-CETSA data acquisition of MCF-7 cells treated with Vehicle (DMSO), Docetaxel or Paclitaxel using TMT 10 plex.

NIAID Data Ecosystem10

Top fifteen hubs in M. tuberculosis that are absent in the metabolome of humans.

分枝杆菌代谢途径

药物靶点发现

*ACP-FAS enzyme involved in the fifth reaction of the mycolic acid pathway ranks as the 38th unique hub in M. tuberculosis.

NIAID Data Ecosystem50

Catalytic Domain of Human Calpain 8

蛋白酶结构解析

药物靶点发现

Catalytic Domain of Human Calpain 8 Descriptor: CALCIUM ION, Calpain-8, Leupeptin Inhibitor Authors: Davis, T.L, Paramanathan, R, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith,

Protein Data Bank Japan2024-10-30 更新30

Adenylation domain of NAD+ dependent DNA ligase from M.tuberculosis

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