Cistrome profiles of Retinoids x Receptor alpha (RXRa) , Retinoic Acid Receptor alpha (RARa), and Retinoic Acid Receptor beta (RARß) in livers of mice treated by control and retionic acid-containing diet

Comparison between ChIP-Seq data of RARa and RARß, between RAR and RXR, as well as between control and retinoic acid-treatment for each investigated nuclear receptors. Overall design: Mouse were treated by control diet and RA-diet for 1 days. After treatment, livers were used to do ChIP using antibodies of RXRa, RARa, and RARß. An aliquote of total chromatin without pull-down process by any antibodies was used as input control. A single-end read of 35bp sequencing was performed on each of ChIPed DNA and input. Sequencing data of RARa and RARß were compared to each other. In addtional, each of RARa and RARß data were compared with RXRa data. For each nuclear receptor, ChIP-Seq data prior or after RA-treatment were also compared with each other.