We carried out whole-genome oxidative bisulfite sequencing (WGoxBS) in the placentas of two healthy female and two healthy male pregnancies generating an average genome depth of coverage of 25x. The s
This directory contains full summary statistics for the following EWAS studies in the Generation Scotland cohort. Epigenome-wide autosomal sites associated with chronological age with concordant effec
Additional File 2: Table S2. Summary of the RNA-seq dataset and the number of expressed genes detected on individual chromosomes at various raw count thresholds. Table S3. List of DMRs. A list of diff
Our findings suggest that gender is underwritten in the epigenome in a tissue-specific manner. Gender-specific epigenetic states are likely to have important implications for understanding sexually di
Purpose: In this study we employed unbiased, genome-wide techniques to identify regulatory elements during murine sex determination. Methods: We performed ATAC-seq on 60K FACS-purified XX and XY gonad