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Crystal structure of YVAD-cmk bound human legumain (AEP) in complex with compound 11

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of YVAD-cmk bound human legumain (AEP) in complex with compound 11 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-(morpholin-4-yl)-2,1,3-benzoxadiazol-4-amine, AC-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, ... Authors: Dall, E, Ye, K, Brandstetter, H. Deposit date: 2016-09-08 Release date: 2017-03-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.27 Å) Cite: Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer's disease. Nat Commun, 8, 2017

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2016-09-08
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