Laboratory parameters and clinical outcomes of the syphilis and control groups.

Note: The quality screening criteria for high-quality embryos included the presence of 7–8 blastomeres of equal size with an accumulation of <20% cell debris by day 3 (Embryology, 2011).
Normally fertilized oocytes were defined as those with two pronuclei (2PN) and 2 polar bodies at 16–20 hours after oocyte retrieval.
The normal fertilization rate was calculated as follows: number of normally fertilized oocytes / (number of oocytes with one pronucleus + number with two pronuclei + number with multiple pronuclei + number with late cleavage).
The implantation rate (IR) was defined as the number of gestational sacs per number of embryos transferred.
The live birth rate per embryos transferred was defined as the total number of births per the number of embryos transferred that resulted in clinical pregnancy.
The clinical pregnancy rate per embryo transferred was determined by the number of patients with a gestational sac in the uterus at 5 weeks after embryo transfer.
Early miscarriage was defined as the natural termination of pregnancy before 12 weeks, even in the presence of a positive serum hCG test or an ultrasound-detected intrauterine gestational sac after embryo transfer.
Biochemical pregnancy was defined as a pregnancy that did not clinically progress, accompanied by a β-hCG level of ≥25 U/L.
a The independent samples t-test was performed to compare the syphilis and control groups, and the values are presented as the mean ± standard deviation.
b A significant difference was detected between the syphilis and control groups using the independent samples t-test (P<0.05).
c The Mann-Whitney test was conducted to compare the non-normally distributed data, and the results are shown as the median (range).
d Data were obtained using Pearson’s chi-square test.
e A significant difference was detected between the syphilis and control groups using Pearson’s chi-square test (P<0.05).
f Data were obtained using Fisher’ Exact Test.
Laboratory parameters and clinical outcomes of the syphilis and control groups.