Microarray analysis of cerebrum specific genes regulated by oxidative stress and aging.

A, Each circle is indicating the numbers of either up or down regulated genes by oxidative stress, aging in the cerebrum and in the cerebellum. Five genes were up-regulated and four genes were down regulated by both oxidative stress and aging in the cerebrum without significant changes in the cerebellum. B, The heat maps of five genes up-regulated and C, four genes down-regulated by oxidative stress and aging. Red indicates up-regulated genes and blue indicates down-regulated genes, while white indicates no significant change in expression. The color gradients indicate the intensity of expression. The data shows the results of four mice per each group. Abbreviation used; OS; oxidative stress.