Structure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity
收藏Protein Data Bank Japan2026-02-18 更新2026-04-19 收录
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Structure-Guided Design of Picomolar-level Macrocyclic TRPC5 Channel Inhibitors with Antidepressant Activity Descriptor: (E)-1-(4-chlorobenzyl)-3-fluoro-1-(3-hydroxypropyl)-1,1,1,1-tetrahydro-1H-2,4-dioxa-1(8,3)-purina-3(1,3)-benzenacyclodecaphane-1,1-dione, CALCIUM ION, Short transient receptor potential channel 5, ... Authors: Che, T, Zhang, J, Xiong, B, Cheng, X.Y. Deposit date: 2025-05-27 Release date: 2025-12-03 Last modified: 2026-02-18 Method: ELECTRON MICROSCOPY (3.23 Å) Cite: Structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity. Acta Pharm Sin B, 16, 2026
创建时间：
2025-05-27
