Bmi1 mutant vs. WT dental epithelia

NIAID Data Ecosystem2026-03-07 收录

牙发育转录组学

干细胞基因调控

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE45999 数据链接链接失效反馈

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资源简介：

Transcriptional profiling of Bmi1 mutant dental epithelia including the stem cell compartment to determine which genes are upregulated in response to loss of Bmi1. Two condition experiment: dental epithelia homozygous null for Bmi1 and WT dental epithelia. 4 replicates each

创建时间：

2013-04-18

Epigenomic profiling studies of murine leukemia stem cell (LSC) lines established ex vivo by coexpression of R882H-mutated DNMT3A and NRAS-G12D (ChIP-seq). Mus musculus

白血病表观遗传学

干细胞基因调控

DNA Methyltransferase 3A (DNMT3A) is frequently mutated in various hematopoietic malignancies; however, the underlying oncogenic mechanisms remain elusive. Here, we report that DNMT3A mutational ‘hots

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Gene expression changes in human cord blood-derived hematopoietic stem and progenitor cells upon Centrifugation enhanced Nanostraw Transfection or Conventional Electroporation. Gene expression changes in human cord blood-derived hematopoietic stem and progenitor cells upon Centrifugation enhanced Nanostraw Transfection or Conventional Electroporation

基因组学技术评估

干细胞基因调控

CD34+ human cord blood-derived cells were subjected to GFP mRNA delivery or mock treatment using Centrifugation enhanced Nanostraw Transfection (CeNT) or conventional electroporation. Overall design:

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Genome-wide analysis revealed a crosstalk between p53 and the pluripotent gene networks in mouse embryonic stem cells (expression)

干细胞基因调控

p53信号通路

Genome-wide analysis revealed a crosstalk between p53 and the pluripotent gene networks in mouse embryonic stem cells (expression)

ChEBI2012-03-05 更新30

Gene regulation and priming by Topoisomerase IIa in embryonic stem cells [FAIRE-Seq]

干细胞基因调控

TopoisomeraseIIa功能

Topoisomerases are essential for resolving topological problems in the genome, while their function in gene regulation, especially during cellular differentiation, remains unknown. We reveal that the

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Transcriptomes of miR-290-295 KO mESCs treated with siPOOLs against the transcription factor Tfap4

干细胞基因调控

miRNA靶标识别

In order to identify direct microRNA targets in mouse embryonic stem cells (mESCs), we knocked out microRNA effector genes, profiled their transcriptomes and integrated the data with additional publis

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Bmi1 mutant vs. WT dental epithelia

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