Differentiation of mouse embryonic stem cells (mESCs) is accompanied by changes in replication timing. To explore the relationship between replication timing and cell fate transitions, we constructed

NIAID Data Ecosystem40

Competition for H2A.Z underlies the developmental impacts of repetitive element de-repression

发育表观遗传学

染色质调控

The histone variant H2A.Z is central to early embryonic development, determining transcriptional competency through chromatin regulation of gene promoters and enhancers. In addition to genic loci, we

NIAID Data Ecosystem40

Genome-wide map of open chromatin, trancription factor occupancy, chromatin marks and gene expression profiles in mouse nephron progenitor cells

发育表观遗传学

多组学整合分析

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate [Isl1_E8_75_RNA_seq]. Pioneering function of Isl1 in the epigenetic control of cardiomyocyte cell fate [Isl1_E8_75_RNA_seq]

发育表观遗传学

心肌细胞谱系定型

Generation of widely differing and specialized cell types from a single totipotent zygote involves large-scale transcriptional changes and chromatin reorganization. Pioneer transcription factors play

NIAID Data Ecosystem40

Developmental dynamic promoter categories across tissues.

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