Mass spectrometry-based characterization of SET1/COMPASS complex in Caenorhabditis elegans
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https://www.omicsdi.org/dataset/pride/PXD029904
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资源简介：
Changes in histone post-translational modifications are associated with aging through poorly defined mechanisms. Histone 3 lysine 4 (H3K4) methylation at promoters is deposited by SET1 family methyltransferases acting within conserved multiprotein complexes known as COMPASS. Using co-immunopurification coupled to mass spectrometry-based proteomics, we characterized complex members and binding partners in various genetic contexts, using WDR-5 or CFP-1 proteins as baits.
创建时间：
2021-12-08
