Cytotoxicity, anti-leishmanial in vitro activity and selectivity index (SI) of TPM 1, TPM 2, TPM 6, TPM 9 and GV against L. (L.) amazonensis and L. (V.) braziliensis on intracellular amastigotes assay.
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IC50 values correspond to mean and 95% CI of results obtained from triplicates; n.d., not determined; data obtained from linear regression on MiniTab® 15.1 software; mean value of parasite growth inhibition observed for control drug (0.2 µg/ml AmB) was 98% for L. (V.) braziliensis and 99.5% for L. (L.) amazonensis.
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2015-12-02
