Additional file 1 of Quantification of [11C]PBR28 data after systemic lipopolysaccharide challenge

Additional file 1: Supplemental Material. Table S1.Figure S1. Mean AIF data are depicted separately for rs6971 genotype HABs (C/C; gray lines) and MABs (C/T; black lines) pre-LPS (solid lines) and post-LPS (dashed lines). Figure S2. Individual values, pre- and post-LPS, are depicted for each brain region for models that incorporate the AIF: A) 2TCM VT; B) 2TCM-1k VT; C) MA-1 VT (t*=30); and D) SIME BPP. The same color marker was used to depict each subject’s data across models and LPS dose (pre- vs. post-LPS). Figure S3. A Time-Activity Curve was extracted from the occipital cortex (OCC) of a representative subject and kinetic model fit are depicted: A) pre-LPS 2TCM; B) post-LPS 2TCM; C) pre-LPS 2TCM-1k; and D) post-LPS 2TCM-1k.