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Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to N-ethylbutyryl-PUGNAc

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of Burkholderia cenocepacia family 3 glycoside hydrolase (NagZ) bound to N-ethylbutyryl-PUGNAc Descriptor: Beta-hexosaminidase, N-[(2Z,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-{[(phenylcarbamoyl)oxy]imino}tetrahydro-2H-pyran-3-yl]-2-ethylbutanamide Authors: Vadlamani, G, Mark, B.L. Deposit date: 2017-02-15 Release date: 2017-04-19 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Conformational flexibility of the glycosidase NagZ allows it to bind structurally diverse inhibitors to suppress beta-lactam antibiotic resistance. Protein Sci., 26, 2017
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2017-02-15
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