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Additional file 11 of Sex specific molecular networks and key drivers of Alzheimer’s disease

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Additional file 11: Supplemental Table 11. The top network drivers of male AD. Candidate genes of the top AD-associated modules in the gene network of the PHG from the male AD subjects in the MSBB cohort and in the gene network of the PFC from the male AD subjects in the ROSMAP cohort. Genes that met any of three selection criteria were selected and further rank-ordered based on the strength of association with AD. The rank order was calculated based on multiple p values calculated from module-trait correlation and module-DEG enrichment analyses with a candidate score which ranges from 0 to 1. Number of the published literature on each specific candidate gene was also shown.
提供机构:
Wang, Minghui; Goate, Alison; Lee, Yeji; Zhou, Xianxiao; Bu, Guojun; Chao, Michael; Huang, Min; Zhang, Bin; Cao, Jiqing; Cai, Dongming; Liu, Chia-Chen; Guo, Lei; Li, Yonghe; Zhu, Li; Duarte, Mariana Lemos; Martens, Yuka; Hou, Jianwei; Haroutunian, Vahram; Zhang, Larry
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2024-08-13
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