Additional file 1 of Plasma metabolic profiles predict future dementia and dementia subtypes: a prospective analysis of 274,160 participants

Additional file 1: Table S1. UKB Nightingale metabolite measurements and clinical parameters information. Table S2. Detailed dementia outcome definition. Table S3. All 249 metabolites baseline characters of the study participants by dementia case-control status. Table S4. Comparison of covariate distributions for 10 regions. Table S5. Results of associations between plasma metabolites and incident dementia. Table S6. Results of associations between plasma metabolites and incident dementia stratified by sex. Table S7. Results of associations between plasma metabolites and incident dementia stratified by age. Table S8. Results of associations between plasma metabolites and incident dementia stratified by APOE4 carrier status. Table S9. Results of metabolites importance ranking. Table S10. The hazard ratios of MetRS in the full cohort and subgroups. Table S11. Discriminative performance of CPH models.