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Loss of H3K27 monomethylation leads to DNA-methylation-independent release of gene silencing

ChEBI2009-05-31 更新2026-07-21 收录

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-16071 数据链接链接失效反馈

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Loss of H3K27 monomethylation leads to DNA-methylation-independent release of gene silencing

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创建时间：

2009-05-31

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甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

Epigenetic gene regulation during astrocyte development

胶质细胞发育

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Numerous literatures report similar time points are important in astrocyte development and transition from neurogenesis to gliogenesis. However, these developmental time points have not been studied i

NIAID Data Ecosystem00

H3 Acetylation and H2A.Z Levels Interplay to Regulate Gene Expression and Plant Development

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发育分子机制

H2A.Z is a conserved histone variant that plays essential roles in various DNA-templated processes across eukaryotes. H2A.Z and histone post-translational modifications (PTMs) exert a bidirectional an

NIAID Data Ecosystem00

Impact of CAR agonist ligand TCPOBOP (27 hr time point) on H3-K27me3 marks in adult male mouse liver

组蛋白修饰ChIP-seq

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Chromatin immunoprecipitation and sequencing for the H3K27me3 histone mark was performed on livers of male mice either treated with vehicle or with TCPOBOP for 27 h. This dataset is part of a larger s

NIAID Data Ecosystem00

A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus [RNA-Seq, HiC_C2C12, ChIP-Seq]

基因组三维结构

表观遗传调控

The binding of the transcriptional regulator CTCF to the genome has been implicated in the formation of topologically associated domains (TADs). However, the general mechanisms of folding the genome i

NIAID Data Ecosystem00

Loss of H3K27 monomethylation leads to DNA-methylation-independent release of gene silencing

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