Crystal Structure of the first bromodomain of BRD4 in complex with acetyl-pyrrole derivative compound 83
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Crystal Structure of the first bromodomain of BRD4 in complex with acetyl-pyrrole derivative compound 83 Descriptor: 1,2-ETHANEDIOL, 2-[4-(3-methyl-4-oxidanylidene-2,5,6,7-tetrahydroisoindol-1-yl)-1,3-thiazol-2-yl]guanidine, Bromodomain-containing protein 4 Authors: Dalle Vedove, A, Cazzanelli, G, Lolli, G. Deposit date: 2023-08-23 Release date: 2024-09-11 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Enhanced cellular death in liver and breast cancer cells by dual BET/BRPF1 inhibitors. Protein Sci., 33, 2024
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2023-08-23
