Hypoxia impact Salmonella adhesion via T1F regulation

In this study we investigate the first stages of Salmonella Typhimurium infection under hypoxia conditions We found that low oxygen levels significantly decrease the bacterium's adhesion level. However, a high-binding phenotype of type 1 fimbriae can compensate for this deficiency. The study also identified a cross-talk between T1F and flagella expression in low-oxygen conditions, suggesting that altered flagellin expression levels may affect the bacterium's motility.