RNA-sequencing of human lung samples derived from COVID-19 patient autopsy. Lung samples derived from COVID-19 patient autopsy. Experiments using samples from human subjects were conducted in accordan

NIAID Data Ecosystem50

Ten Years of Pathway Analysis: Current Approaches and Outstanding Challenges

微生物通路分析

计算生物学方法学

Pathway analysis has become the first choice for gaining insight into the underlying biology of differentially expressed genes and proteins, as it reduces complexity and has increased explanatory powe

NIAID Data Ecosystem40

Prevalence and Mechanisms of Mucus Plugging in COVID-19 Lung Disease

COVID-19肺部病理

黏蛋白表达机制

Purpose: To investigate molecular mechanisms of SARS-CoV-2-induced mucin expression and synthesis and test candidate countermeasures. Methods: Bulk RNA-seq was performed on well-differentiated human b

NIAID Data Ecosystem50

Comparative performance of different methods in identification of relevant biological pathways for balanced datasets.

微生物通路分析

方法性能比较

Comparative performance of different methods in identification of relevant biological pathways for balanced datasets.

Figshare2021-10-06 更新50