This item is part of the Figshare Project : Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution From Data Availability Statement for
Validation was done by dot blot assay with the specific antibodies on single PBMC samples from ALS patients, ALS>24 (n = 20), and non-ALS neurological controls (NC) (n = 23); mean ± SD of the relative
Oxidative stress-induced damage is a major mechanism in the pathophysiology of amyotrophic lateral sclerosis (ALS). A recent human clinical trial showed that the combination of nicotinamide riboside (