The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-571519
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The crystal structure of the large ribosomal subunit from Deinococcus radiodurans complexed with the pleuromutilin derivative SB-571519 Descriptor: (2S,3AR,4R,5S,6S,8R,9R,9AR,10R)-2,5-DIHYDROXY-4,6,9,10-TETRAMETHYL-1-OXO-6-VINYLDECAHYDRO-3A,9-PROP[1]ENOCYCLOPENTA[8]ANNULEN-8-YL [(6-AMINOPYRIDAZIN-3-YL)CARBONYL]CARBAMATE, 23S ribosomal RNA, 50S ribosomal protein L3 Authors: Davidovich, C, Bashan, A, Auerbach-Nevo, T, Yonath, A. Deposit date: 2007-01-07 Release date: 2007-05-01 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity. Proc.Natl.Acad.Sci.Usa, 104, 2007
创建时间:
2007-01-07



