Additional file 1: Table S1. Established genetic variants in the HMGCR, PCSK9 and NCP1L1 gene that mimic statins, PCSK9 inhibitors and ezetimibe respectively]. Table S2. Correlation matrix for genetic
Observed versus expected minor allele frequency for gene polymorphisms associated with statin myalgia in cases versus controls compared to population frequency.
Idelalisib is a phosphatidylinositol 3-kinase inhibitor highly selective for the delta isoform that has shown good efficacy in treating chronic lymphocytic leukemia and follicular lymphoma. In clinica
Results from Genome-wide association study of antidepressant exposure meta-analysis downstream analysis including:Clumping and fine-mapping (OM1_clumps_finemap.xlsx)positional gene mapping (OM2_gene_m
BackgroundStudies of the genetic basis of drug response could help clarify mechanisms of drug action/metabolism, and facilitate development of genotype-based predictive tests of efficacy or toxicity (
