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Candidate Pigmentation Genes.

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Figshare2015-12-02 更新2026-05-11 收录
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Our siRNA-based screening approach identified 98 siRNAs that significantly inhibited pigment production. 4 of these 98 genes did not retest, while two of the 98 genes were removed from the Refseq database. Gene Ontology databases were used to segregate the 92 remaining genes into function classes and identify conserved domains within the corresponding proteins. Gene ontology databases, OMIM, and Pubmed searching was utilized to identify associations between our genes and human diseases. Genes in our candidate list that are aberrantly expressed in MNT-1 cells as compared to normal melanocytes are shown in bold.

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2015-12-02
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