BIOGRID CURATED DATA FOR SWD3 (Saccharomyces cerevisiae (S288c))

Protein-Protein, Genetic, and Chemical Interactions for SWD3 (Saccharomyces cerevisiae (S288c)) curated by BioGRID (https://thebiogrid.org); DEFINITION: Essential subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5

SWD3（酿酒酵母S288c）的蛋白质-蛋白质、遗传和化学相互作用数据集，由BioGRID（https://thebiogrid.org）整理；定义：COMPASS（Set1C）复合体中的必需亚基；COMPASS在赖氨酸4位上甲基化组蛋白H3，并在端粒附近的转录沉默中发挥作用；WD40 β螺旋超家族成员，与哺乳动物的WDR5同源。