Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor
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Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor Descriptor: 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine, Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Authors: Howard, T.D, Ogg, D.T. Deposit date: 2021-12-14 Release date: 2022-05-18 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.39 Å) Cite: Development of Selective Phosphatidylinositol 5-Phosphate 4-Kinase gamma Inhibitors with a Non-ATP-competitive, Allosteric Binding Mode. J.Med.Chem., 65, 2022
创建时间：
2021-12-14
