Clinical characteristics of the external test cohort of patients with MM (TMA 2).

#1Welch two sample t-test,
#2Fisher’s exact test,
#3Multivariate Cox regression,
*p-Value <0.05,
***p-Value <0.001.
Comparing high-risk patients (first column) with low-risk patients (second column) based on their seven-marker risk score showed a significant difference in tumor thickness (p<0.001) and Clark levels (p<0.001), and no difference in sex (p = 1), age (p = 0.267) and nodal status (p = 0.34). Furthermore, hazard ratios and p-values were reported for a multivariate Cox regression model comprising all listed variables. Regarding overall survival the seven-marker risk score was statistically significant (p<0.05) independent of sex, age, nodal status, clark score and tumor thickness. Continuous variables are reported with mean and standard deviation and categorical variables are listed with number of counts and percentages.